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The BARI 2D trial was a landmark study – the first major trial to focus exclusively on patients with both diabetes and heart disease.
Patient follow-up was completed November 30, 2008.
Patient follow-up was completed November 30, 2008.
- BARI 2D, a randomized clinical trial, was designed to compare various treatment strategies for diabetes and heart disease to prevent early death, heart attack and stroke.
- 2368 participants were randomized at 49 sites in 6 countries.
- All subjects were given intensive medical therapy to control cholesterol and blood pressure and given counseling, if needed, to quit smoking and to lose weight.
- Beyond that, we compared whether prompt revascularization, either bypass surgery or angioplasty, e.g. stents, was more effective than medical therapy alone.
- At the same time, we also looked at which of two diabetes treatment strategies resulted in better outcomes—insulin-providing versus insulin-sensitizing - that is, increasing the amount of insulin or making the insulin work better.
- To read more about the study click here.
University of Pittsburgh Epidemiology
Data Center
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